The Amateur Traveler has done 3 episodes on San Francisco and all three advised a fair amount of walking: Soundseeing Tour 1 San Francisco (part 1), Soundseeing Tour 1 San Francisco (part 2), Episode 159 San Francisco, California
San Francisco walking tour map with photos
This city is a wonderful place for photographers no matter what the weather. There is no photo that cannot be improved by a cable car riding by. Besides, taking a picturegives you an excuse to stop walking so that people dont know you are really out of breath from walking the hills.
Map of great photography spots in the San Francisco Bay area
This is the home of Levi Strauss and in many local businesses (high tech not banking) what the east coast thinks is business casual here is considered as dressing up. You can dress nicer for dinner or the theatre but do it because you want to not because you think it is expected.
A Roll of Quarters
San Francisco is a great city to ride public transportation. If all the cars in San Francisco were to stop and try and find parking at the same time there would not be enough places to park. The system only works at all because some people are driving at any time. So kellieparker recommends a roll of quarters for exact change on the bus (fare is $1.50). Cable car fares are $5.00 one way for adults and youth.
MikeTRose says Allergy medications. For some reason, East Coasters like me get the sniffles in SF. It is quite possible that Mike has an allergy to mold or mildew. San Francisco gets wrapped in a blanket of fog most nights and so it can stay pretty damp which can be refreshing or vexing, depending on your expectations. But it is a paradise for molds and people with allergies should take note.